I made my first issue with a computer, with scanned pictures resized etc. But I used a typewriter font... I wanted a handmade look but didn't have any printer or typewriter on that night. I still don't have, but I'm trying to make my second issue totally cut & paste.
i type and draw mine by hand and figure out the layout in a cut and paste kind of way, then i scan them all into photoshop, clean them up a little and make my type darker since my typewriter ribbon is perpetually running out of ink, and make pdf's to send to the printer. sometimes i'll do other digital tweeking, like inverting my handdrawn text so that it's white on black, etc, just to give it more punch. so a little of both i guess.
Cut and Paste all the way!!! I love getting my hands dirty and really spending time getting my layout JUST perfect! As far as my text goes....I go back and forth between handwritting it and typing it on the computer. I like the fact that I can play around with different fonts when typing it up on my puter...but when it comes to the look and layout... I revert back to cutting and pasting with glue sticks.